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Everest Biotech.png

艾美捷科技特约代理Everest Biotech公司产品。


Everest Biotech公司成立于2000年,该公司主要生产山羊抗体,针对人类、小鼠、大鼠等物种的一系列重要的抗原。另外,Everest Biotech公司已通过ISO 9001:2015认证 (Certificate number CA14829),可靠的质量和个性化的服务,使得客户以遍布全球。

 

所有来自Everest Biotech的抗体均有以下特性
(1) Everest Biotech自主研发生产
(2)全部经过肽亲和纯化以保证最佳的特异性和纯度;
(3)经过免疫原肽的ELISA和WB实验验证;
(4)PhD科学家团队,提供全方位技术支持服务。

 

Everest Biotech - Experts in antigen affinity purified goat polyclonal antibodies.  

Since 2000, Everest has been producing a catalog containing thousands of goat antibodies against a broad range of human, mouse and rat proteins of biomedical interest.

 

Everest Biotech's commitment to quality and continuous improvement has been recognised with ISO 9001:2015 accreditation (Certificate number CA14829). The customers can be assured they will receive high quality product and excellent customer service.

 

按疾病种类分:

Allergy

Autoimmunity

Cancer

Cardiovascular

Genetic Disorders

Infectious

Metabolic

Neuronal

 

按生物功能分:

Adhesion

Apoptosis and its regulation

Autophagy

Cell Cycle and DNA Repair

Chromatin, Histone and RNA regulation

CNS and PNS

Cytoskeletal elements

Embryogenesis and cell differentiation

GAP, GBP, GEF. GRP, GTPase proteins

Inflammation

lectins

Lipids and Sterols Pathways

Mitochondrial proteins

Protein integrity, maturation and break down

Protein Kinases

Protein Phosphatases and Inhibitors

Receptors

SH2 domain containing proteins

SH3 domain containing proteins

Transcriptional regulators

Transcription factors

Translation and its regulation

Transporters, protein sorting, channels

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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Everest Biotech
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Immunolab.png

Immunolab GmbH主要从事开发和生产各种免疫诊断试剂,可用于过敏诊断、自身免疫血清学、传染病以及食物分析等领域。在过敏诊断领域,主要产品是一系列综合过敏原的免疫球蛋白IgE、IgG、IgG1和IgG4试剂盒。

 

Founded in 1992, Immunolab started its operations as routine laboratory for allergy diagnostics. The name Immunolab originates from this task, applying immunological methods. Soon we started with the development, production and distribution of our own products. Both, food safety and IVD medical devices were covered from the very beginning. Products and processes were driven by quality thinking which resulted in the accredited establishment of our quality management system in 2002, followed by the accreditation of all IVD products according to the European legislation. As a demand of constant growth we moved to our own facility in 2007, which was extended considerably in 2015 and is equipped according to all modern standards. In 2014 Immunolab joined Biovendor group. This gave us the chance to combine all our experience and flexibility as a smaller-scale company with the opportunities of a larger network of companies.

 

主要产品:

Clinical Diagnostics (human)

Clinical Diagnostics (veterinary)

Food Analytics / Safety

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更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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Immunolab
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Hybrid Plastics.png

艾美捷科技代理Hybrid Plastics全系列倍半硅氧烷POSS化合物。

笼型倍半硅氧烷,具有无机立方核和外部有机基团的有机-无机杂化化合物倍半硅氧烷是一种有机硅化合物,其化学式为[RSiO3/2]n(R=H,烷基,芳基或烷氧基)。倍半硅氧烷是无色固体,采用笼状或聚合结构,具有Si-O-Si键和四面体Si顶点。倍半硅氧烷是多八面体倍半硅氧烷(POSS)的一种,作为陶瓷材料和纳米复合材料的前驱体引起了人们的关注。不同的取代基(R)可以连接到Si中心。这些分子是不寻常的,因为它们具有无机硅酸盐核和有机表面。硅芯具有刚性和热稳定性。

Hybrid Plastics致力于提供全球最高质量的POSS®材料。具有ISO 9001:2008的质量管理体系,艾美捷科技有限公司与Hybrid Plastics Inc.长期合作,致力于为中国用户提供:Acrylates-POSS、Alcohols-POSS、Amines-POSS、Carboxylic Acids-POSS、Epoxides-POSS、Fluoroalkyls-POSS、Halides-POSS、Methacrylates-POSS、Molecular Silicas-POSS、Norbornenyls-POSS、Olefins-POSS、PEGs-POSS、Silanes-POSS、Silanols-POSS、Thiols-POSS等化合物。


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image.png MA0736 Acryloxypropyl POSS Cage mixture  现货销售   image.png



image.png MA0735 Methacryloxypropyl POSS 现货销售   image.png



image.png AM0270 AminopropylIsooctyl POSS 现货销售 image.png


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产品主要包括:

http://www.amyjet.com/Index/lists/catid/27/kid/28.html

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货号品名规格
AL0125 – Trans-cyclohexandiol Isobutyl POSS1kg
AL0130 – 1,2-Propanediolisobutyl POSS1kg
AM0265 – AminopropylIsobutyl POSS100g,500g,1kg
AM0270 – AminopropylIsooctyl POSS100g,500g,1kg
AM0281 (Neat) – N-Phenylaminopropyl POSS25g,50g,100g,500g,1kg
AM0281.01.30 – N-Phenylaminopropyl POSS50g,1kg
EP0408.01.30 – Epoxycyclohexyl ethyl POSS cage mixture 30% PGMEA100g,1kg
EP0409 – Glycidyl POSS cage mixture100g,1kg
EP0409.07.30 – Glycidyl POSS Nanosilica Dispersion1kg
EP3530 – POSS Bond EP35301 Quart, 1 Gallon
HC0304.11 Cyclohexylepoxy Glycidyl POSS
HC0310.31 – Cyclohexylethylepoxy isoOctyl POSS
HC0313.31 – Cyclohexylethylepoxy PEG POSS
HC0407.11 – Glycidyl Methacryl POSS
HC0407.13 – Glycidyl Methacryl POSS
HC0407.31 – Glycidyl Methacryl POSS
HC040713.332 Glycidyl Methacryl PEG POSS
HC0413.53 – Glycidyl PEG POSS
HC0507.53 – Trifluoropropyl Methacrylpropyl POSS
HC0613.53 – Acrylic PEG
HC07051013.2211 Methacrylpropyl Trifluoropropyl iso-Octyl PEG POSS
HC0709.13 Methacrylpropyl iso-butyl POSS
HC0710.13 – Methacryloxypropyl isoOctyl POSS
HC0713.31 – Methacryloxypropyl PEG POSS
HC1110.71 Vinyl iso-Octyl POSS
MA0701 – Acryloxypropyl isobutyl POSS1kg
MA0702 – Methacrylpropyloisobutyl POSS1kg
MA0719 – Methacryloxypropyl isooctyl POSS1kg
MA0735 – Methacryloxypropyl POSS
MA0736 – Acryloxypropyl POSS Cage mixture100g,1kg
MA0735.08.30 – Methacrylic POSS Nanosilica Dispersion
MA0736.08.30 – Acrylic POSS Nanosilica Dispersion
MA0737 – Alpha Methacryl POSS
MS0802 – DodecaPhenyl POSS1kg
MS0805 – OctaIsooctyl POSS1kg
MS0825 – OctaIsobutyl POSS1kg
MS0860 – OctaTMA POSS1kg
PG1190 – MethoxyPEG POSS cage mixture100g,500g,1kg
PG1193 HC1013.31 – MethoxyPEGisoOctyl POSS
PM1270 – Phenyl Silanol Resin100g
SH1310 – Octasilane POSS50g
SO1450 – Trisilanol isobutyl POSS100g,1kg
SO1455 – TriSilanollsooctyl POSS100g,1kg
SO1458 – Trisilanol phenyl POSS100g,1kg
TH1555 – Mercaptopropyl isooctyl POSS50g,100g
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" data-original="http://antibodie.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Hybrid Plastics全系列倍半硅氧烷POSS化合物">
艾美捷科技代理Hybrid Plastics全系列倍半硅氧烷POSS化合物
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Salimetrics.jpg

Salimetrics是一家全球著名的唾液生物学研究领域专业产品供应商,其在唾液的收集方法、生物学性质及其(唾液中各生物组分的含量)定量检测技术拥有绝对的研发与产品供应优势。作为唾液生物学研究及诊断试剂盒应用领域的行业标准,其供应的唾液手机方案及唾液成分的ELISA检测试剂盒均专门唾液的理化性质所设计,可确保客户在科学研究或临床诊断中得到稳定、准确的唾液生物学信息,并同时具有操作简便、结果精确可靠、可重复性高、耗时少等诸多优点。Salimetrics的唾液检测实验室及拥有丰富的唾液生物学研发经验的专业团队可以为广大客户提供唾液生物学研究及诊断应用的专业指导。

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更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com


产品名称

产品编号

产品参数

Salivary 17 Alpha-OHP ELISA Kit

1-2602

Catalog#: 1-2602
  Format: 96-well plate
  Assay Time: ~ 3 hrs
  Sample Volume/Test: 50 µL
  Sensitivity: 3 pg/mL
  Assay Range: 5.1 pg/mL - 500pg/mL
  Storage Requirements: 2-8°C
  Optimum Collection Volume: 125 μL*
  Collect With: SalivaBio Passive Drool
  Serum-Saliva Correlation: 0.64

Salivary Alpha-Amylase Enzymatic Kit

1-1902

Catalog#:1-1902
  Format:96-well plate
  Assay Time:~ 30 mins
  Sample Volume/Test:10 µL of saliva then 8 µL of X200 dilution
  Sensitivity:0.4 U/mL
  Assay Range:2-400 U/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:25 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:NA

Salivary Androstenedione ELISA Kit

1-2902

Catalog#:1-2902
  Format:96-well plate
  Assay Time:~ 3 hrs
  Sample Volume/Test:50 µL
  Sensitivity:5 pg/mL
  Assay Range:10 pg/mL - 2430 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:125 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:NA

Salivary C-Reactive Protein ELISA Kit

1-2102

Catalog#:1-2102
  Format:96-well plate
  Assay Time:~ 5 hrs
  Sample Volume/Test:150 µL of saliva, 100 µL of x2 dilution
  Sensitivity:9.72 pg/mL
  Assay Range:25 pg/mL - 1600 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:225 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:NA

Salivary Cortisol ELISA Kit

1-3002

Catalog#:1-3002
  Format:96-well plate
  Assay Time:~ 2 hrs
  Sample Volume/Test:25 µL
  Sensitivity:<0.007 ug/dL
  Assay Range:0.012-3.000 ug/dL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 uL
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:0.91

Salivary Cotinine ELISA Kit

1-2002

Catalog#:1-2002
  Format:96-well plate
  Assay Time:~ 2.5 hrs
  Sample Volume/Test:20 µL
  Sensitivity:0.15 ng/mL
  Assay Range:0.8 ng/mL - 200 ng/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 µL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:NA

Salivary DHEA ELISA Kit

1-1202

Catalog#:1-1202
  Format:96-well plate
  Assay Time:~ 4 hrs
  Sample Volume/Test:50 µL
  Sensitivity:5 pg/mL
  Assay Range:10.2 pg/mL - 1000 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:125 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.86

Salivary DHEA-S ELISA Kit

1-1252

Catalog#:1-1252
  Format:96-well plate
  Assay Time:~ 2 hrs
  Sample Volume/Test:100 µL
  Sensitivity:43 pg/mL
  Assay Range:188.9 pg/mL- 15,300 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:225 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:NA

Salivary Estradiol ELISA Kit

1-3702

Catalog#:1-3702
  Format:96-well plate
  Assay Time:~ 3 hrs
  Sample Volume/Test:100 µL
  Sensitivity:0.1 pg/mL
  Assay Range:1 pg/mL - 32 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:225 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.80

Salivary Estriol ELISA Kit

1-1802

Catalog#:1-1802
  Format:96-well plate
  Assay Time:~ 3 hrs
  Sample Volume/Test:25 µL
  Sensitivity:16 pg/mL
  Assay Range:20 pg/mL - 4860 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:175 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.87

HS Salivary Estriol ELISA Kit

1-1802

Catalog#:1-1802
  Format:96-well plate
  Assay Time:~ 24 hrs
  Sample Volume/Test:100 µL of X2 dilution
  Sensitivity:1 pg/mL
  Assay Range:5 pg/mL - 1215 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:175 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.87

Salivary Estrone ELISA Kit

1-3202

Catalog#:1-3202
  Format:96-well plate
  Assay Time:~ 4 hrs
  Sample Volume/Test:100 µL
  Sensitivity:1 pg/mL
  Assay Range:3.1 pg/mL - 300 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:255 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:NA

Salivary Interleukin-1 Beta ELISA Kit

1-3902

Catalog#:1-3902
  Format:96-well plate
  Assay Time:~ 4.5 hrs
  Sample Volume/Test:20 µL
  Sensitivity:<0.037 pg/mL
  Assay Range:3.13 pg/mL – 200 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:50 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:NA

Salivary Interleukin-6 ELISA Kit

1-3602

Catalog#: 1-3602
  Format:96-well plate
  Assay Time:~ 4.5 hrs
  Sample Volume/Test:60 µL
  Sensitivity:0.07 pg/mL
  Assay Range:0 – 100 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:135 μL
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:NA

Salivary Melatonin ELISA Kit

1-3402

Catalog#:1-3402
  Format:96-well plate
  Assay Time:~ 4 hrs
  Sample Volume/Test:100 µL
  Sensitivity:1.37 pg/mL
  Assay Range:0.78-50 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:225 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:0.81

Salivary Progesterone ELISA Kit

1-1502

Catalog#:1-1502
  Format:96-well plate
  Assay Time:~ 2 hrs
  Sample Volume/Test:50 µL
  Sensitivity:5 pg/mL
  Assay Range:10 pg/mL - 2430 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:125 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:NA

Salivary Secretory IgA ELISA Kit

1-1602

Catalog#:1-1602
  Format:96-well plate
  Assay Time:~ 4 hrs
  Sample Volume/Test:25 µL
  Sensitivity:2.5 µg/mL
  Assay Range:2.50 µg/mL – 600 µg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:50 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:

Salivary Testosterone ELISA Kit

1-2402

Catalog#:1-2402
  Format:96-well plate
  Assay Time:~ 2 hrs
  Sample Volume/Test:25 µL
  Sensitivity:1 pg/mL
  Assay Range:6.1 pg/mL - 600 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:0.96

Salivary Transferrin/Blood Contamination ELISA Kit

1-1302

Catalog#:1-1302
  Format:96-well plate
  Assay Time:~ 1.5 hrs
  Sample Volume/Test:25 µL
  Sensitivity:<0.007 ug/dL
  Assay Range:0.012-3.000 ug/dL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 μL*
  Sample Test Volume:20 µL
  Collect With:SalivaBio Passive Drool
  Assay Sensitivity:0.08 mg/dL
  Assay Range:0.08 mg/dL - 6.6 mg/dL
  Serum-Saliva Correlation:NA

Salivary Uric Acid Assay Kit

1-3802

Catalog#:1-3802
  Format:96-well plate
  Assay Time:~ 30 mins
  Sample Volume/Test:10 µL
  Sensitivity:0.07 mg/dL LOD
  Assay Range:5 mg/dL (NIST certified)
  Storage Requirements:2-8°C
  Optimum Collection Volume:25 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:0.84

Diagnostic Salivary Cortisol ELISA Kit (FDA, CE   Mark)

1-3102

Catalog#:1-3102
  Regulatory Status:510(k), CE Mark
  Format:96-well plate
  Assay Time:~ 2 hrs
  Sample Volume/Test:25 µL
  Sensitivity:<0.007 ug/dL
  Assay Range:0.012-3.000 ug/dL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 uL
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:0.91

Diagnostic Salivary Cotinine ELISA Kit (FDA, CE   Mark)

1-2112

Catalog#:1-2112
  Regulatory Status:510(k) Exempt, CE Mark
  Format:96-well plate
  Assay Time:~ 2.5 hrs
  Sample Volume/Test:20 µL
  Sensitivity:0.15 ng/mL
  Assay Range:0.8 ng/mL - 200 ng/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 µL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:NA

Diagnostic Salivary DHEA ELISA Kit (CE Mark)

1-2212

Catalog#:1-2212
  Regulatory Status:CE Mark
  Format:96-well plate
  Assay Time:~ 4 hrs
  Sample Volume/Test:50 µL
  Sensitivity:5 pg/mL
  Assay Range:10.2 pg/mL - 1000 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:125 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.86

Diagnostic Salivary Estradiol ELISA Kit (FDA, CE   Mark)

1-3702

Catalog#:1-3702
  Regulatory Status:510(k) Exempt, CE Mark
  Format:96-well plate
  Assay Time:~ 3 hrs
  Sample Volume/Test:100 µL
  Sensitivity:0.1 pg/mL
  Assay Range:1 pg/mL - 32 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:225 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.80

Diagnostic Salivary Estriol ELISA Kit (CE Mark)

1-2812

Catalog#:1-2812
  Regulatory Status:CE Mark
  Format:96-well plate
  Assay Time:~ 24 hrs
  Sample Volume/Test:100 µL of X2 dilution
  Sensitivity:1 pg/mL
  Assay Range:5 pg/mL - 1215 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:175 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:0.87

Diagnostic Salivary Progesterone ELISA Kit (FDA, CE   Mark)

1-2502

Catalog#:1-2502
  Regulatory Status:510(k) Exempt, CE Mark
  Format:96-well plate
  Assay Time:~ 2 hrs
  Sample Volume/Test:50 µL
  Sensitivity:5 pg/mL
  Assay Range:10 pg/mL - 2430 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:125 μL*
  Collect With:SalivaBio Passive Drool
  Serum-Saliva Correlation:NA

Diagnostic Testosterone ELISA Kit (CE Mark)

1-2312

Catalog#:1-2312
  Regulatory Status:CE Mark
  Format:96-well plate
  Assay Time:~2 hrs
  Sample Volume/Test:25 µL
  Sensitivity:1 pg/mL
  Assay Range:6.1 pg/mL - 600 pg/mL
  Storage Requirements:2-8°C
  Optimum Collection Volume:75 μL*
  Collect With:SalivaBio Passive Drool
  SalivaBio Oral Swab (SOS)
  SalivaBio Children's Swab (SCS)
  SalivaBio Infant's Swab (SIS)
  Serum-Saliva Correlation:0.96

< " data-original="http://antibodie.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="Salimetrics">
Salimetrics
...
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Dendritics.jpg

Dendritics公司主要关注人类树突状细胞,希望找到能够促使CD34+造血前体细胞转化为树突状细胞(在GM-CSF和TNF-alpha存在的情况下)的细胞因子。在1992-2005年间,大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

 

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

 

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

 

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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GenWay公司是为了探索和开发人类蛋白组而成立的。公司的总任务就是用基因特异性抗体來筛选和鉴定新蛋白、其功能及其编码基因,旨在成为以抗体介导的蛋白组研发的领域先锋。基因纬公司已成功地发展出一套有自己知识产权的、新穎、高效、低耗、高筛选通量的鉴定方法――抗体介导的蛋白和基因鉴定。公司提供大量的高质量的蛋白和相应的鸡抗体产品,是蛋白质组学研究的重要工具和有力助手。

 

As a leading protein and antibody solutions provider, GenWay has a proprietary technology platform and an international network to provide our clients with solutions and applications for proteins, antibodies, assays, and cell lines. We specialize in recombinant proteins and domain-specific IgY (chicken) antibodies and their applications, such as Seppro® products and difficult-to-express proteins. GenWay’s technology and expertise make high-quality protein antigens that enable production of high-quality antibodies and related applications.

 

GenWay Biotech的主要产品包括:

Proteins

Antibodies

ELISA Kits

Secondary Antibodies

Reagents

Peptides

Molecular Biology Products

Active Proteins

Enzymatic Assays

PCR Kits

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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